Why Painkillers and Anticonvulsants Fail in Chronic Diabetic Neuropathy Introduction Chronic diabetic neuropathy is a persistent and often worsening condition that affects millions of diabetics worldwide. Burning, stabbing, or electric-shock-like pain in the limbs is one of the most disturbing symptoms—and it’s usually addressed with painkillers or anticonvulsants. While these medications may offer short-term relief,
Side Effects of Gabapentin and Pregabalin in Long-Term Use Introduction Gabapentin and pregabalin are among the most commonly prescribed medications for diabetic neuropathy and other forms of chronic nerve pain. These drugs, classified as gabapentinoids, work by modulating nerve activity and reducing pain signals to the brain. Initially marketed as safe alternatives to opioids, they
Limitations of Topical Creams and Nerve Block Injections in Painful Diabetic Neuropathy (PDN) Introduction Painful Diabetic Neuropathy (PDN) is one of the most persistent and distressing complications of long-standing diabetes. Patients often experience burning, electric shocks, stabbing pain, or deep aches in the feet, legs, or hands. In desperation, many turn to topical creams and
Nerve Pain Isn’t Normal – Even If You’ve Had Diabetes for Years Introduction Living with diabetes often brings a quiet surrender: a belief that symptoms like burning feet, tingling hands, or electric pain in the legs are simply part of the disease. Over time, patients are told to “accept” that nerve pain is normal, especially
